Advice Needed: Efficient Glycerol Hit Picking with Hamilton Microlab Prep

Hi Denise,

While my aspirating/dispensing with cold glycerol stock has been limited to Tecans for the time being, I bet some of my learnings could be beneficial and practical for your setup.

  1. Our stocks came in tubes, which we kept cold on deck with Inheco CPAC: compact workstation heater/cooler. Through some additional searching I also found these but we never pursued them: https://ariumlab.com/product-category/cooling-blocks/. You can also mix and match this to have adapters for troughs or more standard SBS labware.

I just found this forum post that the Prep should have Hamilton Heater/Cooler coverage soon so definitely look into that as well: Labware and accessories - #6 by EricSindelar_Hamilton.

  1. Slow aspirate/dispense speeds came to be extremely useful and we had to fine tune these significantly as we found our optimal settings.

  2. We used standard pipetting tips on our Fluent, but I do know that Hamilton sells wide bore tips that could be helpful depending on if you can keep sufficient pressure when aspirating and dispensing.

Happy to help more if I’m able to. Best of luck and hope that helps!

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