Primer guide to everything robotic microscopy - open to feedback!

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hey everyone :wave:, back again with a second primer!

for context, i’m working with @luisvillaautomata and @Jascha on a lab auto hardware hack as part of sf deep tech week june 22-23.

one of the robotic platforms we will have for hackers to build on is a microscope system from hongquan and the cephla team.

to help software developers and hardware engineers go 0 to 1 in robotic microscopy, we made this intro guide. it has 50+ modules covering an intro, workflow, hardware, software, company features, and emerging trends

we see this as a community resource (it’s open access and free to circulate) to help people go 0 to 1 and would appreciate any feedback if you want to take a look.

specifically

  1. general structure and subsections. anything you’d change?
  2. section #7 - any leading companies in 2024 that are missing?
  3. any additional resources for section #9?
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As someone who plans to build a DIY microscope at some point, this is awesome

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Only thing I can think of

  1. Maybe including some popular software that folks that can use to DIY a solution
  2. Does this include plate reading? If so, groups like Byonoy are about as exciting as it gets. I envision that they’ll continue their current trajectory before they release a multimodal reader.
  3. AI debates are so toxic rn in bio but the IMO the most realistic lab gains within the next 3-5 years are in lab automation. I’m talking about the Day-to-Day operations, not just Drug Discovery. DD will get the headlines but using AI as part of our every day toolset (lab auto) is going to become so commonplace. A group who’s doing interesting work here is Chemometec.
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@stefan glad to hear it!

@luisvillaautomata thanks for the feedback! great points and resources.

in response to the feedback:

1 - will explore see if there’s a good resource that lists them and add to the end
2 - i’m making the next one on plate handling, mobile assistants, and think plate reading may fit better in this one v. the micrscope one (definitely debatable though!)
3 - this is one that could fit in between both the microscope primer and plate handling/reading primer. will see how it sits in the next one, and if it seems better for this one, will be sure to include here

longer term, thinking of an automated instruments one too…

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