384-well plate dispensing with CO-RE 96 head

[CamilloMoschner]

@rickwierenga

I think for the quadrants you showed, you’d have to skip alternating columns. The wells are too close otherwise for the 96 head to reach simultaneously. Stefan’s code gives intuition for this.

hehe yeah… I have been using the quadrants I showed for 8-channel processing of 384-well plates and haven’t thought about the column-jumping of the 96-MPH.

Here are the correct quadrants for the 384-well plate using a 96-MPH:

@rickwierenga

@Stefan

For plate based 96 channel references like what PLR uses you can use XY offsets. There might be other ways to do it but that is the most obvious to me.

I don’t think this is very clean tbh. It’s not clear what’s happening when you aspirate_plate with offset=something or even offset=(well.location.x, …). This might work quickly though, so I’d recommend people play with it.

I completely agree with Rick. Offsets are “quick & dirty” solutions and very good if you have to perform an experiment or have a showcase tomorrow but otherwise they are too hacky and lead to confusion in the long-term.
We should figure out a more permanent solution now that the opportunity has arisen.

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A general question regarding the 96-MPH:
How can we use this problem to enable picking up and using non-96 position tip pickups and aspiration dispensations?

E.g. how can the 96-MPH pick up only 4 columns of tips? or 4-columns of tips using only 6 of the 8 possible rows?