Why can’t you dispense into a more automation friendly quadrant layout on the 384w plates?
(visual stolen from 384-well plate dispensing with CO-RE 96 head - #19 by CamilloMoschner )
Are you trying to do this?
How are you supporting 480 samples? A single 384w plate that only ever has one source plate in there? What are you doing for replicates? Is this a 1x 96 → 1x384 w/ 4 replicates and you have 5 plates of each on deck sort of deal?
Going from the layout I understand you to be doing to the one above would save you a lot of time pipetting. It would also enable you to use the 96w head which would save you even more time pipetting. Being able to stamp would make this a 10-20 minute protocol.
If you absolutely can’t change the plate layout (and saving literal hours as a result), the HSLSeqSortingLib mentioned above is definitely the way to go.