Liquid handlers with integrated robotic arms - reliability

Over the past 5 years or so a number of liquid handlers with integrated robotic arms and equipment cabinets have come on to the market. Personally I have experience working with a Vantage system, and my experience has been mostly good. I’ve listed some Pros and Cons below. I’d like to hear about other systems like this (Tecan, Beckman, etc.) and how reliable/useful the standard robotic arms are.

Vantage Pros:

  1. For short methods the Track Gripper is typically reliable
  2. Engineers are generally available to take a look at the system on short notice
  3. Spare parts are covered by service agreement and typically arrive in ~1 week
  4. All components in my system are from Hamilton, so there were no struggles to integrate pieces from various vendors, and no need to have scheduling software

Vantage Cons:

  1. Track gripper tends to error out on longer runs requiring multiple plate moves - makes me nervous to create overly long or complex methods, and recovering from an error can become burdensome
  2. As far as I can tell there is no PM service - arm components can be recalibrated on request if they’re causing an issue, but no preventative maintenance is being done.
  3. Over 3 years we’ve had to replace multiple parts of Track Gripper as they’ve malfunctioned, which worries me in terms of its longevity/reliability

I’ve seen a wide suite of arms now and they all have their problems. Never seen one good-to-go out of the box, and never seen one have 100% success rate over a long time-course (>8 hrs).

The best systems I’ve seen for reliably moving plates are carosel/slider systems with hard fix points to their work surface. Still even these fail (though they seem to reliably fail at the same interactions).

Some simple fixes/smart integrations would help any of these arms work significantly better, but I’ve yet to see any company implement smart changes. Not sure if this is an IP issue or just poor engineering talent for labware design. 30,000 lb concrete blocks can reliably dropped within 1 mm (or less) of eachother yet labware robotic arms struggle to move 30g items reliably.

Guess I’ll just start making my own hardware

1 Like