We have numerous work cells with various methods that must maintain the sterile field on-deck. Our current implementation includes measures like placing VCAPs on main power, battery backups, or generator emergency power to maintain sterility during power cycling or adjustments.
Our issue is that on the Vantage, the loading tray lowers when a method completes. For the Microlab Star with Venus, the End Method command automatically prepares the instrument for the next run, which works well for most tasks like aborting methods or handling errors. However, we want to omit the part of this command that lowers the tray. Ideally, the tray should stay semi-permanently in the raised position unless explicitly lowered within a method. While the tray lowers during power-down due to motor mechanics, our concern is contamination between methods when significant deck space is exposed. Though HEPA filters mitigate most contaminants, adjusting the End Method command to maintain tray position is critical, especially in production environments.
We’ve tried a workaround using a script with a timer that requires users to force-close Run Control, but this is impractical for automated scripts and poor practice overall. The only alternative for critical sterility workflows is using enclosed systems like a STAR or Tecan with a fully sealed deck space. This issue feels like it could be resolved by omitting or modifying a single command, but we’ve been unable to implement this change.
If anyone has successfully adjusted the End Method command in this way or has insights into the issue, your input would be greatly appreciated. Perhaps @EricSindelar_Hamilton knows of clients who’ve requested similar functionality—we feel we can’t be the only team needing this.
