Hello. We are seeing residual volumes in tips with sticky liquids (master mix, beads). I’ve tried various settings (flow rate, blowout, integrated mixing, aspirate/dispense mixing), but still a small amount is lost after each action (0.5-1 uL loss). It can be worse with multiple mix cycles (2-3 uL loss). This does not occur manually. We originally accepted this as a system limitation, but with new sensitive workflow, this loss is impacting the quality of our data.
I don’t want to add too much blowout to introduce air since the volumes are low, forcing a fixed height aspirate.
Using a Vantage (VoV) with standard CORE channels. Eagerly looking for suggestions and solutions. Thanks for your ideas.